Methylsulfonylmethane, more commonly referred to as MSM, is a compound found naturally in humans, plants and animals and can also be produced synthetically for medicinal use. MSM is made by combining Dimethyl Sulfoxide (DMSO) and Hydrogen Peroxide and is a source of sulfur for methionine. Most commonly used for joint conditions, MSM helps to preserve and maintain connective tissues. Its primary role is to reduce inflammation in the body.
On a molecular level, MSM can reduce neutrophil production and therefore also reduce the production of oxidative free radicals. This is how it works as an antioxidant.
MSM is a low-toxicity agent that can safely be used as an anti-inflammatory agent in a number of inflammatory conditions. A major benefit of MSM is that it can be used with most medications, supplements or herbal agents.
Research has shown that MSM is beneficial for gastrointestinal concerns, pain, autoimmune conditions, bladder inflammation and fibromyalgia. Clinical research has found that MSM can help to improve gastrointestinal motility and promote more frequent bowel movements in those individuals more susceptible to constipation. Studies have also shown improvement of Scleroderma with IV MSM treatments, especially when digestive organs are involved. Results have been documented with IV MSM and Rheumatoid Arthritis with improvement in joint stiffness, pain and mobility.
Our patients have benefitted from intravenous MSM for joint inflammation due to Lyme disease or other chronic infection in addition to osteoarthritis and Rheumatoid Arthritis, an autoimmune condition. Another condition in which we have seen patients improve is IV MSM administration in seasonal allergies and asthma. Asthma has an immune system component driven by inflammation, which has been quickly tamed by MSM.
MSM also has the ability to cross the Blood Brain Barrier (BBB), which permits drugs to be carried by MSM and delivered to the brain effectively. Therefore, MSM can work synergistically and increase the effectiveness of drug delivery to the brain.
In this manner, MSM promotes chemoprevention or the prevention of tumor growth by disrupting the tumor cells ability to proliferate through genetic activity. Most commonly, MSM is used along with chemotherapeutic agents.
For more information on intravenous MSM, talk to one of our experienced Naturopathic Doctors.