Allergies

Allergy & Sensitivity Testing: What You Need to Know

Allergic reactions aren’t always obvious. While some may experience immediate and severe symptoms, others live with chronic, low-grade immune responses — like a recurring rash or unexplained fatigue. If you suspect something in your environment or diet is triggering a reaction, but can’t quite identify the culprit, allergy and sensitivity testing can help uncover the cause.

Understanding Immune Reactions

There are three main types of immune-mediated responses to allergens and sensitivities, each involving a different antibody. Knowing which pathway is at work helps guide the appropriate testing and treatment plan.

1. IgE – Immediate Allergic Reactions

IgE is the antibody responsible for “true” allergies.

These reactions are fast and often severe, leading to symptoms like:

• Itchy eyes
• Swelling
• Shortness of breath
• Anaphylaxis

IgE-mediated allergies can be triggered by foods, chemicals, or environmental inhalants (e.g., pollen, dust).

2. IgG – Delayed Food Sensitivities

IgG antibodies are associated with food sensitivities.

These reactions are delayed — symptoms can occur up to 72 hours after exposure.
Symptoms may include:

• Digestive discomfort
• Brain fog
• Fatigue
• Skin issues

IgG testing helps uncover hidden food sensitivities that may be affecting gut and immune health over time.

3. IgA – Mucosal Immune Response

IgA antibodies are produced in mucosal surfaces, especially in the gastrointestinal tract and sinuses.  IgA reactions can play a role in conditions such as leaky gut, sinus inflammation, or chronic digestive issues.

What’s the Difference Between Food Allergies, Sensitivities, and Intolerances?

How We Approach Testing at the Nardella Clinic

Depending on your symptoms, our naturopathic doctors at the Nardella Clinic may recommend testing for IgE, IgG, IgA — or a combination of all three. This allows us to build a comprehensive picture of your immune system’s activity and identify potential triggers in your environment, diet, or lifestyle.

Whether you’re managing hives or headaches, brain fog or bloating — testing can be the first step toward clarity and personalized care.